The use of a series of ketamine infusions in two patients with treatment-resistant depression.
Michael Messer, Irina V Haller, Pamela Larson, Julia Pattison-Crisostomo, Charles E Gessert
The Journal of neuropsychiatry and clinical neurosciences 2010 DOI: 10.1176/jnp.2010.22.4.442 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 2 |
| Population | Two patients with treatment-resistant depression |
| Intervention | Ketamine |
| Topics | Depression Esketamine Ketamine |
| Key findings | The authors report that multiple ketamine treatments may provide an effective rapid antidepressant effect with prolonged benefit in two patients with treatment-resistant depression. |
Abstract
Treatment-resistant depression often leads to increased morbidity and disability. The authors report the use of ketamine, a selective N-methyl-D-aspartate (NMDA) receptor antagonist, in two patients with treatment-resistant depression. Multiple ketamine treatments may provide an effective rapid antidepressant effect with prolonged benefit.