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Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonists.

Neurosci Lett January 27, 2011 DOI: 10.1016/j.neulet.2011.01.046 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Preclinical study Peer reviewed
Topics Serotonin
Key points Argues that the mGlu2 receptor is required for the pharmacological and behavioral effects of hallucinogenic 5-HT2A receptor agonists, indicating a necessary role in mediating these actions.

Abstract

Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonists.