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Decreased accumbens-amygdala connectivity is associated with sleep improvement in late-life depression following mindfulness-based cognitive therapy.

J Affect Disord August 26, 2026 DOI: 10.1016/j.jad.2026.122433 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational study Peer reviewed
Population Older adults with late-life depression
Intervention Mindfulness-based cognitive therapy
Topics Depression Meditation
Key findings Decreased accumbens-amygdala connectivity was associated with sleep improvement following mindfulness-based cognitive therapy in late-life depression, suggesting a neural correlate of treatment response.

Abstract

Decreased accumbens-amygdala connectivity is associated with sleep improvement in late-life depression following mindfulness-based cognitive therapy.