Social hierarchy shapes behavioral and transcriptional responses to chronic stress and ketamine in male mice.
iScience July 21, 2026 DOI: 10.1016/j.isci.2026.116825 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Population | Male mice |
| Intervention | Ketamine |
| Topics | Esketamine Ketamine |
| Key findings | Social hierarchy shapes behavioral and transcriptional responses to chronic stress and ketamine in male mice, suggesting that hierarchical status is an important factor in determining individual responses to stress and antidepressant treatment. |
Abstract
Social hierarchy shapes behavioral and transcriptional responses to chronic stress and ketamine in male mice.