Discordant signals: How outcome measurement shapes interpretation of ketamine response in treatment-resistant depression.
J Affect Disord August 10, 2026 DOI: 10.1016/j.jad.2026.122368 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Topics | Depression Esketamine Ketamine |
| Key points | Argues that the selection of outcome measures significantly affects how ketamine response is interpreted in treatment-resistant depression, with discordant signals across different tools potentially altering conclusions about efficacy. |
Abstract
Discordant signals: How outcome measurement shapes interpretation of ketamine response in treatment-resistant depression.