Mindfulness-Based Interventions for Psychological Stress in Medical Students: A Systematic Review
Ana Leonor Couto, Daniel Humberto Pozza, Ricardo João Teixeira, Isaura Tavares
Healthcare July 2, 2026 DOI: 10.3390/healthcare14131961 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review Randomized Peer reviewed |
|---|---|
| Population | Medical students |
| Interventions | Mindfulness-Based Stress Reduction Compassion Cultivation Training |
| Topics | Meditation |
| Keywords | Psychological intervention Mindfulness-based stress reduction Inclusion mineral Randomized controlled trial Systematic review Protocol science Medline Mental health Clinical psychology Psychological stress Research design Psychological research Meta-analysis Data extraction |
| Key findings | Mindfulness-Based Interventions may reduce psychological stress in medical students, though the evidence is limited by methodological heterogeneity. |
Abstract
Background/Objectives: Medical students are frequently exposed to high levels of psychological stress due to demanding academic workloads and individual responsibilities. Mindfulness-Based Interventions (MBIs) have been increasingly explored as strategies to improve mental well-being of this population. The objective of this systematic review is to evaluate the effects of MBIs on psychological stress among medical students.
Methods: A systematic search of three databases (PubMed, Scopus, and Web of Science) was conducted following PRISMA guidelines upon protocol registration in PROSPERO. Randomized controlled trials (RCTs) and non-randomized studies assessing mindfulness interventions in medical students were included. Risk of bias was evaluated using the Cochrane RoB 2 tool for RCTs and the ROBINS-I tool for non-randomized studies.
Results: Twenty-one studies met the inclusion criteria, including fourteen RCTs and seven non-randomized studies. The types of MBIs were variable between the included studies, including mainly Mindfulness-Based Stress Reduction (MBSR) but also Compassion Cultivation Training (CCT). The interventions were also heterogeneous in what concerns duration and format.
Conclusions: Although further research is required to address current methodological gaps, namely the variable types, formats, and duration of MBIs, this study suggests putative benefits of integrating mindfulness into medical education to promote psychological resilience.
Comparable studies
Other systematic reviews and meta-analyses on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations | 2014 | Meta-analysis | n = 3,515 |
| Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects | 2009 | Systematic review and meta-analysis | |
| The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators | 2012 | Meta-analysis | n = 163 |
| Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission | 2016 | Meta-analysis of individual patient data from randomized controlled trials | n = 1,258 |
| Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials | 2011 | Systematic review |
Citations in the library
Cites 32
- Mindfulness Interventions Annual Review of Psychology September 30, 2016
- Mindfulness-based interventions: an overall review British Medical Bulletin April 21, 2021
- Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Teaching and Learning in Medicine April 1, 2003
- The Empirical Status of Mindfulness-Based Interventions: A Systematic Review of 44 Meta-Analyses of Randomized Controlled Trials Perspectives on Psychological Science February 16, 2021
- Mindfulness interventions in medical education: A systematic review of their impact on medical student stress, depression, fatigue and burnout Medical Teacher November 7, 2017
and 27 more in the library