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The Relationship Between Cannabis, Cognition, and Schizophrenia: It’s Complicated

Hakan Kayır, Jessica Ruffolo, Patrick McCunn, Jibran Y. Khokhar

Current Topics in Behavioral Neurosciences 2022 DOI: 10.1007/7854_2022_396 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics Cannabis CBD
Keywords Effects of cannabis Cognition Schizophrenia object-oriented programming Psychosis Context archaeology Clinical psychology
Citations 15
Key findings Cannabis use is associated with poorer cognition in healthy subjects but better overall cognitive performance in schizophrenia patients, despite being linked to symptom exacerbation and poorer treatment outcomes.

Abstract

America and across the globe. Cannabis use has multifaceted impacts on cognition in schizophrenia patients and healthy subjects. Healthy subjects, particularly those who initiated cannabis use at earlier ages and used high-potency cannabis for longer durations, exhibited poorer cognition mainly in working memory and attention. Cannabis use in schizophrenia has been associated with symptom exacerbation, longer and more frequent psychotic episodes, and poorer treatment outcomes. However, cannabis-using patients have better overall cognitive performance compared to patients who were not cannabis users.

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