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Methoxetamine: prevalence of use in the USA and UK and associated urinary problems

Will Lawn, Rohan Borschmann, A. Cottrell, Adam Winstock

October 7, 2014 DOI: 10.3109/14659891.2014.966345 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Cross-sectional online survey
Sample size 22,289
Population Online survey respondents in the USA and UK (2012 survey)
Key findings Methoxetamine use increased in the USA but decreased in the UK from 2011 to 2012. Among methoxetamine users in 2012, 23.0% reported urinary symptoms, and symptom prevalence was associated with frequency of past-month methoxetamine use, though prior ketamine use could not be excluded as a cause.

Abstract

Background: Methoxetamine is a novel psychoactive substance and a legal alternative to ketamine in many countries, including parts of the United States. Frequent recreational ketamine use can cause lower urinary tract symptoms, whereas methoxetamine was originally marketed as “bladder friendly”.Aims: (1) To determine changes in prevalence of methoxetamine use between 2011 and 2012 in the USA and UK and (2) to investigate the prevalence of urinary symptoms in group of methoxetamine users, who had also used ketamine at least once in their lifetime.Methods: Cross-sectional, anonymous online surveys exploring patterns of drug use were conducted in late 2011 (n = 15 200) and late 2012 (n = 22 289).Results: Reported lifetime, past 12 months, and last month methoxetamine use significantly increased in the USA between 2011 and 2012; whereas, during the same period, past 12 months and last month methoxetamine use significantly decreased in the UK. Of the methoxetamine users questioned in the 2012 survey, 23.0% (n = 98) reported experiencing urinary symptoms. Prevalence of at least one urinary symptom was related to frequency of methoxetamine use in the last month.Conclusions: Methoxetamine use appeared to increase in the United States and decrease in the UK between 2011 and 2012. Approximately, one-quarter of methoxetamine users questioned reported urinary symptoms; however, previous ketamine use cannot be ruled out as the cause of the symptoms.