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β2-Adrenergic Receptor Activation Suppresses the Rat Phenethylamine Hallucinogen-Induced Head Twitch Response: Hallucinogen-Induced Excitatory Post-synaptic Potentials as a Potential Substrate.

Front Pharmacol February 8, 2018 DOI: 10.3389/fphar.2018.00089 (opens in new tab) via PubMed Central

Summary

AI-generated from the abstract

Activating the β2-adrenergic receptor reduces the head-twitch response in rats caused by the phenethylamine hallucinogen DOI. This suggests that hallucinogen-induced excitatory post-synaptic potentials may serve as a neural substrate for this behavior.

Study at a glance

Characteristics Experimental study Peer reviewed
Population Rats
Intervention β2-adrenergic receptor activation
Key finding Β2-adrenergic receptor activation suppresses the head-twitch response induced by a phenethylamine hallucinogen in rats.

Abstract

β2-Adrenergic Receptor Activation Suppresses the Rat Phenethylamine Hallucinogen-Induced Head Twitch Response: Hallucinogen-Induced Excitatory Post-synaptic Potentials as a Potential Substrate.

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