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Effects of Yoga Nidra on Stress, Anxiety, and Depression: A Systematic Review and Meta-Analysis.

Shashank Ghai, Pawel Odyniec, Ishan Ghai

Annals of the New York Academy of Sciences February 1, 2026 DOI: 10.1111/nyas.70149 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review and meta-analysis Peer reviewed
Sample size 5,201
Population Participants in studies of Yoga Nidra for mental health
Intervention Yoga Nidra
Topics Meditation Anxiety Depression
Keywords Yoga nidra Holistic care Mental health Non‐sleep deep rest
Key findings Yoga Nidra showed significant moderate-to-large effects on stress, anxiety, and depression, but low study quality suggests these effects may be inflated.

Abstract

The global mental health crisis has escalated to unprecedented levels, with stress, anxiety, and depression posing major public health concerns. Conventional interventions have shown limited success in addressing these multifaceted issues, prompting researchers to explore alternative solutions. Yoga Nidra (YN), a meditative practice, has gained momentum over the past decade as a potential holistic approach to mental health care. Yet, its clinical effectiveness remains inadequately understood. This systematic review and meta-analysis rigorously assessed YN's impact on stress, anxiety, and depression. A comprehensive search of seven databases and one trial database yielded 814 articles, of which 73 studies involving 5201 participants met the inclusion criteria. Between-group meta-analyses revealed significant benefits of YN for stress (Hedge's g: -0.80 with active comparator, -1.70 with no comparator), anxiety (active: -1.35, no comparator: -1.43), and depression (active: -0.69, no comparator: -0.92). Within-group analyses supported these effects, reinforcing YN's therapeutic potential. However, given the low methodological quality and variability in intervention delivery, these moderate-to-large effects should be interpreted cautiously, as they likely reflect inflated estimates. Despite these limitations, YN shows potential in managing mental health symptoms, underscoring the need for high-quality, standardized research to establish its efficacy as a viable clinical intervention.

Comparable studies

Other systematic reviews and meta-analyses on anxiety, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Research Review: The effects of mindfulness‐based interventions on cognition and mental health in children and adolescents – a meta‐analysis of randomized controlled trials Children and adolescents 2018 Systematic review and meta-analysis n = 3,666
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Patients with cancer- or illness-related anxiety and depression, major depressive... 2020 Systematic review n = 188
Does Mindfulness Meditation Improve Anxiety and Mood Symptoms? A Review of the Controlled Research Clinical populations with medical and emotional disorders 2007 Systematic review n = 15
Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years Patients from included clinical trials 2016 Systematic review

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