Effects of Transcranial Magnetic Stimulation on Body Perception: No Evidence for Specificity of the Right Temporo-Parietal Junction.
Jérôme Daltrozzo, Boris Kotchoubey, Fatma Gueler, Ahmed A. Karim
Brain Topography September 1, 2016 DOI: 10.1007/s10548-016-0496-0 (opens in new tab) via PubMed
Summary
AI-generated from the abstractInhibitory repetitive transcranial magnetic stimulation (rTMS) at 1 Hz increased the frequency of abnormal body perceptions (ABP) compared to excitatory 15 Hz rTMS in 35 healthy adults, but the stimulation site—right temporo-parietal junction (rTPJ) versus a control site—did not affect ABP frequency. Responses to an own-body transformation task were slower with 1 Hz than 15 Hz rTMS, also regardless of site. ABP from rTMS at either site was accompanied by electroencephalographic power decreases across all frequencies at left anterior and central cortical sites. These results suggest that inhibitory rTMS can induce ABP, but the rTPJ may not have a specific role in this process.
Study at a glance
| Characteristics | Experimental study Peer reviewed |
|---|---|
| Sample size | 35 |
| Population | Healthy adults |
| Intervention | repetitive transcranial magnetic stimulation |
| Keywords | EEG Perception Somatosensory processing Transcranial magnetic stimulation Vestibular system |
| Key finding | Inhibitory 1 Hz rTMS increased abnormal body perception frequency and delayed own-body transformation task responses compared to excitatory 15 Hz rTMS, but the stimulation site (rTPJ vs. control) did not affect these outcomes. |
Abstract
Previous data suggest that the right temporo-parietal junction (rTPJ) may have a specific role in abnormal body perception (ABP), including out-of-body experience. We tested this hypothesis with inhibitory (1 Hz) and excitatory (15 Hz) repetitive transcranial magnetic stimulation (rTMS) of the rTPJ and a control site (CS, 5 cm posterior to the rTPJ along the lateral sulcus direction in Brodmann area 19R) in 35 healthy adults. ABP frequency was higher with 1 Hz than with 15 Hz rTMS but unaffected by the rTMS site (rTPJ/CS). Response to an own-body transformation task were delayed with 1 Hz compared to 15 Hz rTMS but also unaffected by rTMS site. ABP from rTMS at both sites induced electroencephalographic power decrease in all frequencies at left anterior and central cortical sites. Our data suggest that inhibitory rTMS can lead to ABP. However, the rTPJ may not play a specific role in this process.