MDMA for PTSD and beyond: a new paradigm brings hope.
Frontiers in Human Neuroscience December 11, 2024 DOI: 10.3389/fnhum.2024.1475013 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Commentary Peer reviewed |
|---|---|
| Topics | Psychedelic-assisted therapy MDMA PTSD |
| Keywords | PTSD Treatment Mental health breakthrough MDMA Research Trauma healing |
| Citations | 3 |
| Key points | Argues that the mental health crisis, worsened by insurance costs, social stressors, COVID-19, and workforce shortages, has left PTSD with few treatment options—the last new FDA-approved treatment was 24 years ago—and suggests that inadequate funding may partly stem from the high prevalence of PTSD among women and disadvantaged groups. |
Abstract
We are experiencing a mental health crisis of unprecedented proportions. Over the last two decades this crisis grew from a perfect storm of rising insurance deductibles, escalating social stressors, the COVID-19 pandemic, and a critical workforce deficiency. Perhaps no mental health arena has a greater shortfall of effective treatment options than Post-traumatic Stress Disorder (PTSD) as the last new treatment was approved by the FDA 24 years ago (Hamner and Davis, 2024). Inadequate funding for research efforts and public resources available to expandservices may in part stem from the inordinate prevalence of PTSD among women anddisadvantaged populations.
Citations in the library
Cited by 2
Cites 11
- Psychedelics Promote Structural and Functional Neural Plasticity Cell Reports June 1, 2018
- MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study. Nature Medicine June 1, 2021
- MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial. Nature Medicine October 1, 2023
- LSD-induced entropic brain activity predicts subsequent personality change. Human Brain Mapping May 6, 2016
- MDMA-assisted psychotherapy for PTSD: Are memory reconsolidation and fear extinction underlying mechanisms? Progress in Neuro-Psychopharmacology and Biological Psychiatry June 8, 2018
and 6 more in the library