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The feasibility of mindfulness-based relapse prevention for adults with substance use disorders (illicit drugs) in a Chinese population: A pilot randomized controlled trial.

Ka Tsun Ting, Ivan Chun Him Leung, Dicken Cheong-Chun Chan, Ken On Tai Yu, Wai Kwong Tang, Fu Chan, Alan Ka Lam Tang, Helen Shuk Wah Ma, Benjamin Hon Kei Yip, Daisy Dexing Zhang, Sarah Bowen, Samuel Yeung Shan Wong

Addiction April 30, 2026 DOI: 10.1111/add.70441 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Pilot randomized controlled trial Pilot study Peer reviewed
Sample size 81
Population Chinese adults with substance use disorder (illicit drugs only) recruited from residential detox centers, community addiction counseling centers, and specialized addiction treatment clinics in Hong Kong
Interventions Mindfulness-based relapse prevention (MBRP) treatment as usual
Duration 1-hour orientation session followed by 2-hour weekly MBRP sessions for 8 weeks; assessments at baseline, immediately after MBRP, and 3- and 6-month follow-up
Topics Addiction Meditation
Keywords Humans Substance-related disorders Feasibility studies Pilot projects Adult Middle aged Hong kong Female Secondary prevention East asian people Chinese Illicit drug Mbrp Mindfulness‐based relapse prevention
Key findings MBRP was feasible in this Chinese population, with high course satisfaction and attendance and retention rates comparable to previous trials. No statistically significant between-group differences were found for craving, depression, anxiety, mindfulness, or health-related quality of life; the authors note only improvement trends in self-efficacy at post-intervention and in addiction severity and psychological flexibility at six months, and conclude there was limited evidence of abstinence efficacy.

Abstract

Background and

Aims: Mindfulness-based relapse prevention (MBRP) has been shown to be beneficial to individuals with substance use disorder (SUD) in the West. The current pilot study aimed at testing the feasibility of MBRP in a Chinese population.

Design: This pilot study adopted a design of randomized controlled trial comparing MBRP with treatment-as-usual group (TAU).

Setting: Participants were recruited from residential detox centers, community addiction counseling centers and substance abuse clinics specialized addiction treatment clinics in Hong Kong.

Participants: A total of 81 adults (85.2% male) with SUD (illicit drugs only) were recruited.

Interventions: The intervention group participants (n = 41) attended a 1-hour orientation session followed by 2-hour weekly MBRP sessions for 8 weeks, delivered by a qualified MBRP teacher. The TAU group participants (n = 40) continued their service received from their referral agency. (After completion of all study assessments they were offered the same 8-week MBRP course.)

Measurements: Feasibility was measured by attendance, course satisfaction and retention rate. Participants' change in substance use and other related outcomes were captured by self-reported drug use, urine drug tests and a list of psychometric scales at baseline, immediately after MBRP and 3- and 6-month follow-up.

Findings: The MBRP course satisfaction was high, and the attendance (57.4%) and retention rates (63.4%-85.4%) were comparable to previous trials. No statistically significant differences were observed between the MBRP and TAU groups for any outcomes, including craving, depression, anxiety, mindfulness and health-related quality of life; however, improvement trends were noticed in the MBRP group in self-efficacy in managing high-risk situations at post intervention, as well as in addiction severity and psychological flexibility at the 6-month follow-up.

Conclusions: Mindfulness-based relapse prevention was shown to be feasible for substance use disorder treatment in a Chinese population. In this small study there was only limited evidence of abstinence efficacy, and no evidence of a benefit on other secondary outcomes.

Comparable studies

Other randomized controlled trials on addiction, most cited first.

Study Year Design Participants
Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder Adults aged 25–65 with DSM-IV alcohol dependence and at least 4 heavy drinking days in... 2022 Randomized controlled trial n = 95
Ketamine psychotherapy for heroin addiction: immediate effects and two-year follow-up. Detoxified heroin-addicted patients 2002 Randomized controlled trial n = 70
A Single Ketamine Infusion Combined With Motivational Enhancement Therapy for Alcohol Use Disorder: A Randomized Midazolam-Controlled Pilot Trial. Adults with alcohol dependence engaged in motivational enhancement therapy 2019 Randomized controlled trial n = 40
A Single Ketamine Infusion Combined With Mindfulness-Based Behavioral Modification to Treat Cocaine Dependence: A Randomized Clinical Trial. Cocaine-dependent adults 2019 Randomized controlled trial n = 55
Single Versus Repeated Sessions of Ketamine-Assisted Psychotherapy for People with Heroin Dependence Detoxified inpatients with heroin dependence 2007 Randomized controlled trial n = 59

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