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Meditation and spiritual practices in mental health: A comprehensive literature review

U Vijayabanu, Aswathi Bimal

International Journal of Applied Research 2026 DOI: 10.22271/allresearch.2026.v12.i3sa.13665 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review Randomized Peer reviewed
Population Clinical and non-clinical populations
Interventions Mindfulness Based Stress Reduction yoga based interventions Transcendental Meditation loving kindness practices mantra chanting
Topics Anxiety Meditation
Keywords Transcendental meditation Mental health Psychological intervention Mantra Guided imagery Psychosocial Psychotherapist Clinical psychology Gratitude Psychological resilience Spirituality Mindfulness meditation Meaningful life
Key findings Meditation and related spiritual practices are moderately effective interventions for common mental health difficulties, roughly comparable to other established psychosocial approaches and non-inferior to first-line pharmacotherapy for anxiety disorders.

Abstract

Meditation and spiritual practices have moved from the margins of medical interest into the center of contemporary mental health research, with a rapidly growing body of randomized trials, neuroimaging studies, and systematic reviews. Evidence from programs such as Mindfulness Based Stress Reduction, yoga based interventions, Transcendental Meditation, loving kindness practices, and mantra chanting suggests meaningful benefits for stress, anxiety, depression, quality of life, and resilience across clinical and non clinical populations [1]. Neurobiological work links these outcomes to changes in cortical structure, default mode net- work activity, stress hormone regulation, inflammatory pathways, and in some cases markers of cellular aging [4]. At the same time, heterogeneity in study quality, the presence of publication bias, and inconsistent control conditions complicate interpretation. Overall, current open access evidence supports meditation and related spiritual practices as moderately effective interventions for common mental health difficulties, roughly comparable to other established psychosocial approaches, and in some cases non inferior to first line pharmacotherapy for anxiety disorders [3].

Comparable studies

Other narrative reviews on meditation, most cited first.

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