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Cross-validation of the ego dissolution scale: implications for studying psychedelics.

Steven Jay Lynn, Charlie W. McDonald, Fiona G. Sleight, Richard E. Mattson

Frontiers in Neuroscience December 5, 2023 DOI: 10.3389/fnins.2023.1267611 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Cross-sectional validation study Peer reviewed
Sample size 527
Population Adults recruited online
Topics Ego dissolution
Keywords Psychedelics Consciousness research Altered states
Citations 8
Key findings The Ego Dissolution Scale has a two-factor structure (Ego-Loss and Unity) with adequate reliability and strong convergent validity with related psychological measures, but not with neuroticism or social desirability.

Abstract

Introduction: Ego dissolution, variously called Ego-Loss, self-loss, and ego disintegration, is a hallmark of psychedelic drug use. We cross-validated the 10-item Ego Dissolution Scale, which we developed to assess ego dissolution in everyday life, and we included comparator variables that expanded our original assessment of construct validity.

Methods: = 527) completed the measures online.

Results: We replicated the original two factor structure (i.e., subfactors: Ego-Loss and Unity/connectedness with others, the world, universe), and we determined that the total score (Cronbach's α = 0.79) and subfactors (Ego-Loss = 78; Unity = 0.83) possessed adequate-to-good reliability and strong convergent validity (e.g., mindfulness, hallucination-predisposition, sleep variables, personality variables, positive/negative affect transliminality, dissociation/depersonalization), while neuroticism, social desirability did not correlate highly with ego dissolution. We identified distinct patterns of relations of measures associated with the Ego-Loss vs. Unity subfactors.

Discussion: We discuss the implications of the use of the EDS for studying everyday aspects of ego dissolution, the long-term effects of psychedelic use, and the value of using the scale in conjunction with measures of the acute effects of psychedelics.

Comparable studies

Other cross-sectional and survey studies on ego dissolution, most cited first.

Study Year Design Participants
Naturalistic use of psychedelics is related to emotional reactivity and self-consciousness: The mediating role of ego-dissolution and mystical experiences Adults with varying histories of psychoactive substance use, including 1661... 2022 Cross-sectional survey n = 2,516
Linkages between Psychedelics and Meditation in a Population-Based Sample in the United States. American adults 2023 Cross-sectional survey n = 953
Losing the Self in Near-Death Experiences: The Experience of Ego-Dissolution. Near-death experiencers with NDE-C scale total score ≥27/80 2021 Survey n = 100
Phenomenological assessment of psychedelic induced experiences: Translation and validation of the German Challenging Experience Questionnaire (CEQ) and Ego-Dissolution Inventory (EDI) German-speaking adults with psychedelic experiences 2021 Cross-sectional psychometric validation study
Embracing change: impermanence acceptance mediates differences in death processing between long-term ayahuasca users and non-users. Ayahuasca veterans and non-users 2025 Cross-sectional study n = 107

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