The Intricate Interaction Between Expectations and Therapeutic Outcomes of Psychedelic Agents
Luana Colloca, Sina Nikayin, Gerard Sanacora
JAMA Psychiatry September 1, 2023 DOI: 10.1001/jamapsychiatry.2023.1412 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Key points | Argues that expectations significantly influence the outcomes of psychedelic drug therapy. |
Abstract
This Viewpoint explores how expectations influence outcomes of psychedelic drug therapy.
Citations in the library
Cited by 17
- Expectancy Effects in Psychedelic Trials. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging May 1, 2024
- Current Perspectives on the Clinical Research and Medicalization of Psychedelic Drugs for Addiction Treatments: Safety, Efficacy, Limitations and Challenges. CNS Drugs October 1, 2024
- Psilocybin: From Psychiatric Pariah to Perceived Panacea American Journal of Psychiatry 2025
- Clinical and preclinical evidence of psilocybin as antidepressant. A narrative review Progress in Neuro-Psychopharmacology and Biological Psychiatry 2025
- Sex-specific role of the 5-HT2A receptor in psilocybin-induced extinction of opioid reward. Nature Communications November 20, 2025
and 12 more in the library
Cites 4
- Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo Neuron July 5, 2021
- Blinding and expectancy confounds in psychedelic randomized controlled trials Expert Review of Clinical Pharmacology May 26, 2021
- Preparing for the Bursting of the Psychedelic Hype Bubble. JAMA Psychiatry October 1, 2022
- Evaluation of Early Ketamine Effects on Belief-Updating Biases in Patients With Treatment-Resistant Depression JAMA Psychiatry September 28, 2022