Synthetic Cannabinoids: History, Chemistry, and Pharmacology
January 5, 2019 DOI: 10.64239/pi-vl1302 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Key points | Synthetic cannabinoids activate the CB1 receptor much more strongly than THC and may cause more intense and longer-lasting intoxication and withdrawal syndromes. |
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Abstract
Synthetic cannabinoids activate the cannabinoid CB1 receptor much more strongly than THC, the primary psychoactive component of plant cannabis. Intoxication and withdrawal syndromes may be more intense and longer lasting than those associated with plant cannabis. Synthetic cannabinoids are typically smoked or inhaled after vaporization (known as vaping).