Cannabis and Psychosis.
Michelle L West, Shadi Sharif
Child and Adolescent Psychiatric Clinics of North America October 1, 2022 DOI: 10.1016/j.chc.2022.07.004 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Population | Young people |
| Topics | Cannabis |
| Key findings | Cannabis use increases risk for psychotic symptoms and may exacerbate psychosis in young people with underlying risk or disorders, but evidence-based treatments for co-occurring conditions are lacking. |
Abstract
Psychosis and cannabis use may overlap in multiple ways in young people. Research suggests that cannabis use increases risk for having psychotic symptoms, both attenuated (subthreshold) and acute. Cannabis use may also exacerbate psychosis symptoms among young people with underlying psychosis risk and psychotic disorders. Although there are suggestions for treating co-occurring psychosis and cannabis use in young people (e.g., incorporating cannabis use assessment and treatment strategies into specialized early psychosis care), there are many gaps in clinical trial research to support evidence-based treatment of these overlapping concerns.
Comparable studies
Other narrative reviews on cannabis, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Causal association between cannabis and psychosis: examination of the evidence | 2004 | Review | |
| Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history. General (historical and pharmacological review) | 2018 | Review | |
| Psychiatric effects of cannabis | 2001 | Review | |
| Beyond THC: The New Generation of Cannabinoid Designer Drugs | 2011 | Review | |
| Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug | 2006 | Review |
Citations in the library
Cited by 2
- The Paradoxical Effect of Cannabis Use on Cognition in Chronic Psychotic Disorders Pathophysiology January 27, 2026
- Occasional cannabis use is associated with higher premorbid functioning and IQ in youth at clinical high-risk (CHR) for psychosis: Parallel findings to psychosis cohorts Schizophrenia Research July 30, 2024
Cites 21
- High-potency cannabis and the risk of psychosis The British Journal of Psychiatry November 30, 2009
- Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment Journal of Psychopharmacology October 5, 2012
- Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study BMJ March 1, 2011
- Cannabis Use during Adolescent Development: Susceptibility to Psychiatric Illness Frontiers in Psychiatry 2013
- Impact of cannabis use on thalamic volume in people at familial high risk of schizophrenia The British Journal of Psychiatry September 9, 2011
and 16 more in the library