Phytochemical analyses of Banisteriopsis caapi and Psychotria viridis.
James C. Callaway, Glacus S. Brito, Edison S. Neves
Journal of Psychoactive Drugs June 1, 2005 DOI: 10.1080/02791072.2005.10399795 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational study Peer reviewed |
|---|---|
| Sample size | 68 |
| Population | Banisteriopsis caapi and Psychotria viridis plants from 22 sites in Brazil |
| Topics | Ayahuasca |
| Key findings | Alkaloid distribution varied widely across samples; all B. caapi contained harmine, harmaline, and THH, while some P. viridis had little or no DMT. |
Abstract
A total of 32 Banisteriopsis caapi samples and 36 samples of Psychotria viridis were carefully collected from different plants on the same day from 22 sites throughout Brazil for phytochemical analyses. A broad range in alkaloid distribution was observed in both sample sets. All B. caapi samples had detectable amounts of harmine, harmaline and tetrahydroharmine (THH), while some samples of P. viridis had little or no detectable levels of N,N-dimethyltryptamine (DMT). Leaves of P. viridis were also collected from one plant and analyzed for DMT throughout a 24-hour cycle.
Comparable studies
Other observational and cohort studies on ayahuasca, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Patients with a depressive disorder | 2015 | Observational study | |
| The Psychedelic State Induced by Ayahuasca Modulates the Activity and Connectivity of the Default Mode Network Experienced subjects | 2015 | Observational cohort | n = 10 |
| Human Psychopharmacology of Hoasca, A Plant Hallucinogen Used in Ritual Context in Brazil Long-term members of a syncretic church that uses hoasca as a psychoactive sacrament... | 1996 | Observational cohort with matched controls | n = 30 |
| Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Rural aboriginal population | 2013 | Observational study | |
| Personality, Psychopathology, Life Attitudes and Neuropsychological Performance among Ritual Users of Ayahuasca: A Longitudinal Study Regular ayahuasca users and active controls in non-ayahuasca religions | 2012 | Observational cohort | n = 242 |
Citations in the library
Cited by 49
- Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Current Drug Abuse Reviews June 1, 2013
- Risk assessment of ritual use of oral dimethyltryptamine (DMT) and harmala alkaloids Addiction December 20, 2006
- Chemical evidence for the use of multiple psychotropic plants in a 1,000-year-old ritual bundle from South America. Proceedings of the National Academy of Sciences June 4, 2019
- Analysis of toxic alkaloids in body samples. Forensic Science International March 10, 2009
- Acute Biphasic Effects of Ayahuasca PLoS One September 30, 2015
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