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Mental Health Facilities With Ketamine Infusion Therapy in the United States in 2020: Co-Location of Dual Diagnosis Mental Health and Substance Use Disorder Treatment

Orrin D. Ware

Carolina Digital Repository (University of North Carolina at Chapel Hill) October 9, 2024 DOI: 10.17615/rd8y-nq91 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Cross-sectional survey Peer reviewed
Sample size 134
Population U.S. mental health treatment facilities that provide ketamine infusion therapy
Topics Ketamine Addiction Esketamine
Keywords Mental health Dual diagnosis Dual grammatical number Substance use
Key findings Approximately 63% of mental health treatment facilities offering ketamine infusion therapy also provide dual diagnosis treatment for co-occurring mental health and substance use disorders.

Abstract

Ketamine is an anesthetic that has been identified as an effective therapy for depressive disorders and related symptoms. Some studies have identified ketamine as having the potential to reduce substance use among individuals with a substance use disorder (SUD)-alongside psychotherapy. Further, SUDs often co-occur with depressive disorders. Using the National Mental Health Services Survey 2020, this study examined a national sample of N = 134 U.S. mental health treatment facilities that provide ketamine infusion therapy (KIT) to identify their geographic locations; availability of individual, couples/family, and group counseling; payment options; and capacity to provide treatment for dually diagnosed mental health (MH) and substance use disorders. Approximately 63% (n = 85) of the facilities in this sample had dual diagnosis MH and SUD treatment. Having group therapy was associated with having dual diagnosis MH and SUD treatment. Alternatively, accepting Medicaid was not associated with having dual diagnosis MH and SUD treatment. This exploratory study estimates dual diagnosis MH and SUD treatment availability among MH treatment facilities offering KIT. Given evidence of KIT's ability to effectively treat depressive disorders and that SUDs often co-occur with them (ketamine's effectiveness in treating substance use disorders warrants further study), the present study's up-to-date information about the distribution salient characteristics of MH facilities that offer this effective treatment can inform future efforts to identify the potential of these facilities to treat co-occurring disorders with ketamine and psychotherapy.

Comparable studies

Other cross-sectional and survey studies on ketamine for addiction, most cited first.

Study Year Design Participants
Self-reported prevalence of dependence of MDMA compared to cocaine, mephedrone and ketamine among a sample of recreational poly-drug users Global non-treatment-seeking sample of last year users of MDMA, cocaine, mephedrone,... 2014 Cross-sectional survey
Differences between users' and addiction medicine experts' harm and benefit assessments of licit and illicit psychoactive drugs: Input for psychoeducation and legalization/restriction debates. German substance-dependent adults seeking inpatient detoxification or rehabilitation... 2022 Cross-sectional comparative study n = 117
Associations between substance use treatment and ketamine use: A hypothesis-generating analysis. U.S. residents aged 12 and older who reported substance use 2026 Cross-sectional survey analysis n = 173,808
Recreational Ketamine Use among Individuals with Opioid Use Disorder: Demographics, Motivations, and Polysubstance Use. Treatment-seeking individuals with opioid use disorder 2025 Cross-sectional survey n = 301
Ketamine Dependence: Clinical Characteristics of an Inpatient Detoxification Population With Complex Physical Health Needs Patients admitted for ketamine detoxification at the Chapman Barker Unit, a regional... 2026 Retrospective cross-sectional study n = 59

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