KETAMINE AS A POSSIBLE MODERATOR OF HYPNOTIZABILITY: A Feasibility Study
David R Patterson, C. Hoffer, M. Jensen, S. Wiechman, S. Sharar
International Journal of Clinical and Experimental Hypnosis June 1, 2018 DOI: 10.1080/00207144.2018.1460559 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Pilot study Peer reviewed |
|---|---|
| Population | Healthy volunteers who scored low on the Stanford Clinical Hypnotizability Scale |
| Intervention | low-dose ketamine |
| Dose | low dose |
| Topics | Esketamine Ketamine |
| Citations | 8 |
| Key points | Ketamine produced changes in dissociation and hypnotizability in the predicted direction, warranting further investigation. |
Abstract
Abstract This pilot study explored the feasibility of using ketamine to increase hypnotizability scores. Ketamine, classified as a dissociative hallucinogen, is used clinically as an anesthetic in high doses and as a treatment for chronic pain and depression in lower doses. Low-dose ketamine can contribute to dissociation and heightened perceptions and feelings of detachment, arguably hypnotic-like states. The authors predicted that a low dose of ketamine in healthy volunteers who scored in the low hypnotizable range on the Stanford Clinical Hypnotizability Scale would (a) cause an increase in subjective ratings of dissociation and (b) lead to an increase in hypnotizability. The findings were in the predicted direction, warranting further investigation into the use of this agent to increase hypnotizability.
Comparable studies
Other non-randomized and open-label trials on ketamine, most cited first.
Citations in the library
Cited by 4
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Cites 4
- Measurement of dissociative states with the Clinician‐Administered Dissociative States Scale (CADSS) Journal of Traumatic Stress 1998
- Psychedelic Effects of Ketamine in Healthy Volunteers Anesthesiology 1998
- Do the dissociative side effects of ketamine mediate its antidepressant effects? Journal of Affective Disorders February 18, 2014
- Effect of ketamine dose on self-rated dissociation in patients with treatment refractory anxiety disorders Journal of Psychopharmacology October 1, 2017