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Efficacy and Safety of Esketamine Nasal Spray Plus an Oral Antidepressant in Elderly Patients With Treatment-Resistant Depression—TRANSFORM-3

July 27, 2020 DOI: 10.64239/pi-qt1701 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial
Population Patients 65 or older
Interventions Nasal esketamine antidepressant
Topics Depression Esketamine
Key findings Nasal esketamine did not outperform placebo in patients 65 or older when initiated with a new antidepressant.

Abstract

Nasal esketamine did not outperform placebo in a randomized trial in patients 65 or older when initiated along with a new antidepressant.