Case of Cardiac Arrest Treated with Extra-Corporeal Life Support after MDMA Intoxication
Pierre Voizeux, Romain Lewandowski, Theresa Daily, Omar Ellouze, Olivier Bouchot, Belaïd Bouhemad, Pierre-Grégoire Guinot
Case Reports in Critical Care January 26, 2020 DOI: 10.1155/2019/7825915 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A 22-year-old man with serotonin syndrome due to MDMA ingestion |
| Interventions | Extra-corporeal life support vasoactive drugs renal replacement therapy mechanical ventilation |
| Duration | First week of hospitalisation |
| Topics | MDMA |
| Citations | 7 |
| Key findings | Extracorporeal life support effectively managed hemodynamic instability in a patient with serotonin syndrome-induced refractory cardiac arrest. |
Abstract
Objective. To describe the case of a patient who developed a serotonin syndrome due to a 3,4-methylenedioxymethamphetamine ingestion with electrical storm and refractory cardiac arrest. Design. Case report. Study Selection. ICU of a university hospital. Patient. A 22-year-old man transferred to the emergency room with hyperthermia, tremors, and mydriasis presented a cardiac arrest due to ventricular fibrillation. Interventions. We implemented extra-corporeal life support combined with vasoactive drugs. Later, he also benefited from renal replacement therapy and mechanical ventilation. Measurements and Main Results. We were able to rapidly regulate our patient’s temperature and we weaned all hemodynamic support in the first week of hospitalisation. Conclusion. Extracorporeal life support has several advantages as part of the management of hemodynamic instability induced by serotonin syndrome.
Comparable studies
Other case reports and case series on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| 'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA Individuals whose deaths were associated with MDMA or MDEA use | 1987 | Case series | n = 5 |
| Pathology of deaths associated with "ecstasy" and "eve" misuse. Young white men aged 20 to 25 who died after using ring-substituted amphetamines (MDMA... | 1996 | Case series | n = 7 |
| 'Eve' and 'Ecstasy' Individuals who died after using MDMA or MDEA | 1987 | Case series | n = 5 |
| A Method of Conducting Therapeutic Sessions with MDMA Clients with clear therapeutic purpose, excluding those with serious functional... | 1998 | Case study | n = 2 |
| Diversity of Psychopathology Associated with use of 3,4-Methylenedioxymethamphetamine (‘Ecstasy’) Psychiatric patients presenting between 1990 and 1992 whose symptoms developed in the... | 1994 | Case series | n = 13 |
Citations in the library
Cites 6
- Serotonin toxicity involving MDMA (ecstasy) and moclobemide Forensic Science International May 20, 2011
- MDMA toxicity: management of acute and life-threatening presentations. British journal of nursing June 14, 2018
- A Case of MDMA-Associated Cerebral and Pulmonary Edema Requiring ECMO. Case Reports in Critical Care 2017
- Ecstasy use and serotonin syndrome: a neglected danger to adolescents and young adults prescribed selective serotonin reuptake inhibitors. International journal of adolescent medicine and health 2013
- Metabolites of MDMA induce oxidative stress and contractile dysfunction in adult rat left ventricular myocytes. Cardiovascular toxicology March 2009
and 1 more in the library