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[Treatment of New Daily Persistent Headache With Esketamine: Report of One Case].

Li Zhang, Jiao He, Cheng-Hui Pi, Ming-Jie Zhang, Zhao Dong

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae August 1, 2024 DOI: 10.3881/j.issn.1000-503X.15842 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population Patient with refractory new daily persistent headache
Intervention Esketamine
Dose sub-anesthetic dose
Topics Esketamine
Keywords Deep brain stimulation Headache therapy Headache management Esketamine ketamine Ketamine therapy Intractable pain Brain disorders Medical
Citations 1
Key findings Intravenous esketamine at a sub-anesthetic dose was used to treat a case of refractory new daily persistent headache.

Abstract

New daily persistent headache (NDPH) is a kind of persistent headache that patients can identify the exact date of the sudden onset.It is one of the rare primary headaches difficult to be cured and may lead to disability,seriously affecting the daily life and work.The exact pathogenesis of NDPH remains unclear,which makes the treatment difficult.Here we report a case of refractory NDPH treated by intravenous injection of esketamine at a sub-anesthetic dose.

Comparable studies

Other case reports and case series on esketamine, most cited first.

Study Year Design Participants
Electroconvulsive Therapy, Ketamine, and Esketamine in a Patient with Major Depressive Disorder and Multiple Comorbidities: A Case Report over 10-year Treatment from Adolescence to Adulthood. A patient with treatment-resistant depression and comorbid generalized anxiety... 2025 Case report n = 1
Oral Administration of the NMDA Receptor Antagonist S-Ketamine as Add-On Therapy of Depression: A Case Series Four depressed patients taking standard antidepressants 2009 Case series n = 4
Effects of intranasal (S)-ketamine on Veterans with co-morbid treatment-resistant depression and PTSD: A retrospective case series Veterans with co-morbid depression and PTSD 2022 Retrospective case series n = 35
Case report: Intramuscular ketamine or intranasal esketamine as a treatment in four patients with major depressive disorder and comorbid anorexia nervosa Patients with anorexia nervosa and a comorbid depressive disorder treated at a private... 2023 Case report n = 4
Repeated oral esketamine in patients with treatment resistant depression and comorbid posttraumatic stress disorder Patients with treatment-resistant depression and comorbid PTSD 2023 Case series n = 5

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