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Effects of Personalized Nursing Combined With Mindfulness-Based Stress Reduction on Anxiety, Depression, and Quality of Life in Patients With Pneumonia-Induced Sepsis.

Xinrong Zheng, Qijun Zhang, Hesheng Zhuang

Actas Españolas de Psiquiatría June 15, 2026 DOI: 10.62641/aep.v54i3.2212 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Retrospective study Peer reviewed
Sample size 127
Population Patients with pneumonia-induced sepsis
Interventions Personalized nursing Mindfulness-Based Stress Reduction (MBSR)
Duration Delivered daily or several times per week until discharge
Topics Anxiety Depression Meditation
Key points Personalized nursing combined with MBSR was associated with significantly greater reductions in anxiety and depression and significantly greater improvements in self-efficacy, quality of life, and self-care ability compared with routine nursing alone.

Abstract

This study aimed to investigate the effects of personalized nursing combined with Mindfulness-Based Stress Reduction (MBSR) on anxiety, depression, self-efficacy, quality of life and self-care ability in patients with pneumonia-induced sepsis. This retrospective study enrolled 127 patients with pneumonia-induced sepsis admitted between July 2023 to July 2024. Among them, 59 patients in the routine nursing group received routine nursing care, while 68 patients in the combined nursing group received personalized nursing combined with MBSR. Routine nursing included vital signs monitoring, oxygen therapy, medication management, basic daily care, nutritional support, health education and complication prevention. The combined nursing group additionally received personalized nursing (e.g., psychological assessment and support, targeted health education, and dynamic adjustment of care plans) and MBSR training (e.g., mindful breathing, body scanning, mindfulness meditation and relaxation training), delivered daily or several times per week until discharge. Outcome measures included the Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD), General Self-Efficacy Scale (GSES), World Health Organization Quality of Life-100 (WHOQOL-100), and Exercise of Self-Care Agency (ESCA), assessed before and after nursing measures. Categorical variables were compared using the chi-square test, and continuous variables (mean ± standard deviation) were analysed using independent-samples t tests. No statistically significant baseline differences in demographic or clinical characteristics were observed between the two groups (p > 0.05). After nursing measures, both groups showed improvements in HAMA, HAMD, GSES, WHOQOL-100, and ESCA scores compared with baseline. The combined nursing group demonstrated significantly greater reduction in HAMA and HAMD scores(p < 0.05) and significantly greater increases in GSES, WHOQOL-100, and ESCA scores(p < 0.05) than the routine nursing group. An integrated approach combining personalized nursing and MBSR was associated with lower levels of negative emotional states, higher self-efficacy in disease management, and better quality of life and self-care ability in patients with pneumonia-induced sepsis. These findings suggest that this nursing model may represent a feasible and potentially beneficial strategy for improving psychological and functional outcomes in clinical practice.

Comparable studies

Other observational and cohort studies on anxiety, most cited first.

Study Year Design Participants
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders Patients with generalized anxiety disorder or panic disorder with or without agoraphobia 1992 Observational cohort n = 22
Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Patients with a depressive disorder 2015 Observational study
Patterning of Cognitive and Somatic Processes in the Self-Regulation of Anxiety: Effects of Meditation versus Exercise Regular practitioners of physical exercise or meditation 1978 Retrospective study n = 77
Dynamic coupling of whole-brain neuronal and neurotransmitter systems Healthy humans 2020 Observational study
Psychedelics not linked to mental health problems or suicidal behavior: A population study Randomly selected United States adults 2015 Observational cohort n = 135,095

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