Spotlight commentary: REBUS and the anarchic brain.
Tehseen Noorani, Ben Alderson-Day
Neuroscience of Consciousness 2020 DOI: 10.1093/nc/niaa007 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Topics | Default mode network |
| Keywords | Rebus Altered states Context Predictive processing Psychedelic |
| Citations | 8 |
| Key points | Argues that the REBUS model of psychedelic action should incorporate greater attention to contextual factors and that comparisons with non-psychedelic altered states may overlook more informative parallels. |
Abstract
In 'REBUS and the Anarchic Brain: Towards a Unified Model of the Brain Action of Psychedelics', Carhart-Harris and Friston offer an important analysis of what the predictive processing framework has to offer our understanding of psychedelic experiences, providing an invaluable ground for psychedelic psychiatry. While applauding this, we encourage paying greater attention to contextual factors shaping extreme experiences and their sequalae, and suggest that the authors' comparisons with certain non-psychedelic altered states may overlook more informative parallels that can be drawn elsewhere. Addressing both points will prove fruitful, ultimately, in identifying the mechanisms of action of greatest interest in psychedelic experiences.
Comparable studies
Other theoretical and historical papers on default mode network, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| The entropic brain: a theory of conscious states informed by neuroimaging research with psychedelic drugs | 2014 | Theoretical or philosophical paper | |
| The default mode network in cognition: a topographical perspective | 2021 | Theoretical or philosophical paper | |
| The default mode network: where the idiosyncratic self meets the shared social world | 2021 | Theoretical or philosophical paper | |
| The default-mode, ego-functions and free-energy: a neurobiological account of Freudian ideas | 2010 | Theoretical or philosophical paper | |
| Cooperation between the default mode network and the frontal–parietal network in the production of an internal train of thought | 2011 | Theoretical or philosophical paper |
Citations in the library
Cited by 9
- Hallucinations Under Psychedelics and in the Schizophrenia Spectrum: An Interdisciplinary and Multiscale Comparison Schizophrenia Bulletin August 5, 2020
- Models of Psychedelic-Assisted Psychotherapy: A Contemporary Assessment and an Introduction to EMBARK, a Transdiagnostic, Trans-Drug Model Frontiers in Psychology June 2, 2022
- Psychedelics, Sociality, and Human Evolution Frontiers in Psychology September 29, 2021
- Uncovering Psychedelics: From Neural Circuits to Therapeutic Applications Pharmaceuticals January 19, 2025
- How Level is the 'Cognitive Playing Field'? Philosophy and the Mind Sciences April 19, 2022
and 4 more in the library