Psychedelic researchers’ own experiences of psychedelic substances, their link to opinions of psychedelics, and reflections on positionality
Jussi Jylkkä, Aila Mustamo
Psychopharmacology August 11, 2025 DOI: 10.1007/s00213-025-06871-2 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Sample size | 111 |
| Population | Psychedelic researchers in academic settings |
| Topics | Psilocybin |
| Keywords | Hallucinogen Link geometry Psychoanalysis |
| Citations | 1 |
| Key findings | Personal use of psychedelics among researchers predicts more positive opinions about psychedelics' potential to improve well-being, transform society, address the ecological crisis, and answer spiritual questions. |
Abstract
Rationale: Anecdotal evidence suggests that psychedelic researchers often have personal experiences with psychedelic substances. While such experiences may benefit research, concerns have been raised about potential biases and "excessive enthusiasm." However, the prevalence of personal experiences, their perceived relevance, and their association with opinions about psychedelics remain underexplored.
Objectives: This study aimed to investigate how common personal psychedelic experiences are among psychedelic researchers, their perceived relevance to research, and whether personal use is associated with opinions about psychedelics.
Methods: Participants (N = 111) conducting psychedelic research in academic settings were recruited. Data were collected on personal experiences, their perceived relevance, and opinions about psychedelics. Regression analyses examined associations between personal use and opinions.
Results: Most respondents (85%) reported personal experiences with classic psychedelics. On average, they saw personal experience as beneficial for research, but also as potential source of bias. They acknowledged the importance of self-reflection and the need to disclose personal experiences, but found disclosure challenging in practice. Personal use predicted more positive opinions about psychedelics' potential to improve well-being, transform society, address the ecological crisis, and answer spiritual questions (regression βs = 0.3 - 0.5, ps < 0.01).
Conclusions: The findings highlight the prevalence of personal psychedelic experiences among this sample of researchers and their influence on research interests and opinions. The results underscore the need for open discussion and reflection. Future studies should explore whether the observed associations reflect causal relationships or potential biases.
Comparable studies
Other observational and cohort studies on psilocybin, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms. Patients with treatment-resistant depression | 2017 | Observational cohort | n = 19 |
| Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels Healthy volunteers | 2019 | Observational cohort | n = 8 |
| Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD and psilocybin Humans | 2017 | Observational study | |
| Classic psychedelic use is associated with reduced psychological distress and suicidality in the United States adult population. USA adult respondents from the National Survey on Drug Use and Health (2008-2012) | 2015 | Observational cohort | n = 190,000 |
| Prediction of Psilocybin Response in Healthy Volunteers Healthy volunteers | 2012 | Observational cohort | n = 409 |
Citations in the library
Cited by 4
- Working with post-psychedelic difficulties: a meta-aggregation of users’ experiences and implications for counselling practice Counselling Psychology Quarterly September 27, 2026
- Analyzing the concept of independence in psychedelic research. Accountability in research May 1, 2026
- Ethics of psychedelics in clinical research: a state-of-the-field review JME Practical Bioethics October 9, 2026
- Understanding treatment expectations toward emerging therapies in veterinary medicine: the role of knowledge, attitudes, and beliefs toward psychedelic-assisted interventions Frontiers in Veterinary Science July 28, 2026
Cites 22
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- Long-term effects of psychedelic drugs: A systematic review Neuroscience & Biobehavioral Reviews March 16, 2020
- The antipodes Of the mind November 7, 2002
- Developing Guidelines and Competencies for the Training of Psychedelic Therapists Journal of Humanistic Psychology June 29, 2017
- Psychedelics alter metaphysical beliefs. Scientific Reports November 23, 2021
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