Updated Findings on the Efficacy of Combined Subanesthetic Ketamine Infusion and Cervical Sympathetic Blockade as a Symptomatic Treatment of PTSD/TBI in a Special Forces Patient with a 2-year Follow-up: A Case Report.
Eugene Lipov, Zubin Sethi, Hunter Rolain
Journal of special operations medicine : a peer reviewed journal for SOF medical professionals April 30, 2025 DOI: 10.55460/2QC5-PHPF (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | Special Operations Forces patient with PTSD and blast traumatic brain injury |
| Interventions | Cervical sympathetic blockade Ketamine infusion |
| Duration | 720 days |
| Topics | PTSD Esketamine Ketamine |
| Keywords | Sof Btbi Cervical sympathetic blockade Ketamine infusion Military-medicine Trauma-treatment Combat-injuries PTSD-Therapy Neurology |
| Key findings | The SOF method provided prolonged and sustained benefits for PTSD and bTBI symptoms over 720 days. |
Abstract
Posttraumatic stress disorder (PTSD)/blast traumatic brain injury (bTBI) in a Special Operations Forces (SOF) cohort has been shown to be successfully treated using a cervical sympathetic blockade (CSB)/ketamine infusion (KI) combination, termed the SOF method. In a prior case report, the patient was followed for 1 year. This report followed the same patient for a total of 720 days and found prolonged and sustained benefits with respect to PTSD and bTBI symptoms with further application of the SOF method.
Comparable studies
Other case reports and case series on ketamine for PTSD, most cited first.