5-Iodo-2-aminoindan (5-IAI): chemistry, pharmacology, and toxicology of a research chemical producing MDMA-like effects.
Maurizio Coppola, Raffaella Mondola
Toxicology Letters March 27, 2013 DOI: 10.1016/j.toxlet.2013.01.008 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | MDMA |
| Citations | 20 |
| Key findings | 5-IAI, a rigid analogue of p-iodoamphetamine producing MDMA-like effects, was identified in recreational products in the UK in 2011. |
Abstract
In 2010, an internet snapshot of EMCDDA anticipated the presence of 5-iodo-2-aminoindan (5-IAI) within the recreational drug market. In 2011, this compound, a psychoactive derivative of 2-aminoindane, was identified in recreational products sold in the United Kingdom. 5-IAI is a rigid analogue of p-iodoamphetamine producing MDMA-like effects. The aim of this paper is to summarize the clinical, pharmacological, and toxicological information about this new potential drug of abuse.
Comparable studies
Other narrative reviews on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Human Pharmacology of MDMA | 2004 | Review | |
| Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research | 2001 | Review | |
| 3,4‐Methylenedioxymethamphetamine (MDMA, “Ecstasy”): pharmacology and toxicology in animals and humans | 1994 | Review | |
| (±)3,4-Methylenedioxymethamphetamine (‘Ecstasy’)-Induced Serotonin Neurotoxicity: Studies in Animals | 2000 | Review | |
| Amphetamine toxicities | 2010 | Review |
Citations in the library
Cited by 2
Cites 17
- Amphetamine toxicities Annals of the New York Academy of Sciences January 8, 2010
- Brain mechanisms of hallucinogens and entactogens Dialogues in Clinical Neuroscience December 31, 2001
- Suspected and Confirmed Fatalities Associated With Mephedrone (4-Methylmethcathinone, “Meow Meow”) in the United Kingdom Journal of Clinical Psychopharmacology August 25, 2012
- Nonneurotoxic tetralin and indan analogs of 3,4-(methylenedioxy)amphetamine (MDA) Journal of Medicinal Chemistry February 1, 1990
- Neurotoxicity of Ecstasy (MDMA): An Overview Current Pharmaceutical Biotechnology June 27, 2010
and 12 more in the library