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5-Iodo-2-aminoindan (5-IAI): chemistry, pharmacology, and toxicology of a research chemical producing MDMA-like effects.

Maurizio Coppola, Raffaella Mondola

Toxicology Letters March 27, 2013 DOI: 10.1016/j.toxlet.2013.01.008 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics MDMA
Citations 20
Key findings 5-IAI, a rigid analogue of p-iodoamphetamine producing MDMA-like effects, was identified in recreational products in the UK in 2011.

Abstract

In 2010, an internet snapshot of EMCDDA anticipated the presence of 5-iodo-2-aminoindan (5-IAI) within the recreational drug market. In 2011, this compound, a psychoactive derivative of 2-aminoindane, was identified in recreational products sold in the United Kingdom. 5-IAI is a rigid analogue of p-iodoamphetamine producing MDMA-like effects. The aim of this paper is to summarize the clinical, pharmacological, and toxicological information about this new potential drug of abuse.