Conclusions to Ketamine
May 14, 2019 DOI: 10.64239/pi-vl1408 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review |
|---|---|
| Topics | Esketamine Ketamine |
| Key findings | Ketamine rapidly improves mood for up to a week or more after a single dose, but long-term safety is unknown. |
Abstract
Ketamine has been shown to rapidly improve mood within a few hours or days of administration. This effect can last for a week or more following a single administration of ketamine. The safety of long-term ketamine exposure is not well known. Future research is urgently needed to better understand long-term risks as well as evidence-based treatment regimens.
Comparable studies
Other narrative reviews on ketamine, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms | 2018 | Review | |
| Mechanisms of Ketamine Action as an Antidepressant | 2018 | Review | |
| Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation Adults with treatment-resistant depression | 2021 | Review | |
| Ketamine Pharmacology: An Update (Pharmacodynamics and Molecular Aspects, Recent Findings) | 2013 | Review | |
| A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders | 2017 | Review and consensus statement |