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Machine learning recovers folk classification of Banisteriopsis caapi from herbarium leaves an ayahuasca liana

Scheila Cristina Biazatti, Deborah Bambil, Rômulo Môra, Lúcio Flávio de Alencar Figueiredo, Regina Célia de Oliveira

iScience April 15, 2026 DOI: 10.1016/j.isci.2026.115753 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational study Peer reviewed
Population A single plant species
Topics Ayahuasca
Keywords Liana Herbarium Ethnobiology Biological classification Perspectivism Artificial intelligence Machine learning Ecology Botany
Key findings Machine learning analysis of morphological variation within a single species partially validates traditional ethnobotanical classifications.

Abstract

reflects morphological overlap. Confusion matrix and similarity network analyses showed only partial agreement with previous ethnobotanical classifications. Focusing on subtle variation within a single species, this study demonstrates that integrating traditional knowledge with machine learning enables automated validation of folk taxonomies.

Comparable studies

Other observational and cohort studies on ayahuasca, most cited first.

Study Year Design Participants
Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Patients with a depressive disorder 2015 Observational study
The Psychedelic State Induced by Ayahuasca Modulates the Activity and Connectivity of the Default Mode Network Experienced subjects 2015 Observational cohort n = 10
Human Psychopharmacology of Hoasca, A Plant Hallucinogen Used in Ritual Context in Brazil Long-term members of a syncretic church that uses hoasca as a psychoactive sacrament... 1996 Observational cohort with matched controls n = 30
Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Rural aboriginal population 2013 Observational study
Personality, Psychopathology, Life Attitudes and Neuropsychological Performance among Ritual Users of Ayahuasca: A Longitudinal Study Regular ayahuasca users and active controls in non-ayahuasca religions 2012 Observational cohort n = 242

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