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Ayahuasca use and improvements in suicidal behavior: An exploratory qualitative study

Nádia Valéria Moreira Santos, Cristiane Ferreira Silveira, Camila Gutieres Dos Santos Soares Costa, Helena Palavro Basso, Paulo César Ribeiro Barbosa, Paulo Rogério Morais

Psychedelics May 16, 2026 DOI: 10.1016/j.psyche.2026.100023 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Qualitative study Peer reviewed
Sample size 9
Population Adults from North and Southeast regions of Brazil who participated in ayahuasca ceremonies in neoshamanic contexts
Intervention Ayahuasca
Topics Ayahuasca
Keywords Exploratory research Qualitative research Poison control Suicide prevention Clinical psychology Psychotherapist
Key findings Ceremonial ayahuasca use in neoshamanic traditions was associated with reduced suicidal ideation and behavior.

Abstract

Aim: This study aimed to explore the experiences and perceived effects of ayahuasca ceremonies on suicidality.

Method: We conducted in-depth qualitative interviews with nine participants from the North and Southeast regions of Brazil. These participants were part of a larger cohort and were selected to explore their perspectives on how ceremonial experiences with ayahuasca in neoshamanic contexts influenced the reduction of suicidal ideation and behavior.

Results: The interviews yielded three main thematic categories related to the therapeutic process of ceremonial ayahuasca use on suicidality: (1) motivations for seeking ayahuasca; (2) post-ayahuasca strategies for strengthening psychological well-being; and (3) the psychedelic experience and its perceived health benefits.

Conclusions: Our findings suggest that the ceremonial use of ayahuasca within neoshamanic traditions can have positive effects on suicidality. Furthermore, these practices may represent emerging and promising psychedelic-assisted care models that may be particularly valuable for communities lacking access to advanced medical treatment.

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