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Set and Setting for Psychedelic Harm Reduction

Ido Hartogsohn

Psychedelic Harm Reduction 2026 DOI: 10.1007/7854_2024_509 (opens in new tab)

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AI-extracted from the abstract
Characteristics Theoretical or philosophical paper Peer reviewed
Topics Psychedelic-assisted therapy
Keywords Clinical trials Harm reduction Psychedelics Recreational use Ritual Set and setting
Citations 13
Key points Proposes that integrating set and setting principles into harm reduction strategies and public health policies could increase safety and benefits across therapeutic, clinical trial, ritualistic, and recreational psychedelic use modalities.

Abstract

Set and setting is a fundamental concept in the field of psychedelic studies, denoting the crucial importance of context to determining the character and quality of experiences with psychedelics. This paper suggests a framework for thinking of set and setting and its relevance for psychedelic harm reduction. It discusses how “set,” the diverse factors related to an individual’s mindset, and “setting,” the diverse environmental dimensions, influence the psychedelic experience and its outcomes, and the relevance to the field of harm reduction. It additionally provides an overview of four basic modalities of set and setting, the therapeutic, the clinical trial, the ritualistic, and the recreational, examining the differences in set and setting between each and the other according to several key parameters, the implications of such differences, and the ways in which harm reduction strategies informed by the principles of set and setting can be integrated to increase safety and benefits in each case. The integration of set and setting principles into public health policies, alongside education on their significance, could further the efficacy of harm reduction programs in the field of psychedelics.

Comparable studies

Other theoretical and historical papers on psychedelic-assisted therapy, most cited first.

Study Year Design Participants
Theorizing that Psychedelic Assisted Therapy May Play a Role in the Treatment of Trauma-Induced Personality Disorders. 2024 Theoretical or philosophical paper
Learning to Let Go: A Cognitive-Behavioral Model of How Psychedelic Therapy Promotes Acceptance 2020 Theoretical or philosophical paper
Awe: a putative mechanism underlying the effects of classic psychedelic-assisted psychotherapy 2018 Theoretical or philosophical paper
Ethical and legal issues in psychedelic harm reduction and integration therapy 2021 Theoretical or philosophical paper
Towards psychedelic apprenticeship: Developing a gentle touch for the mediation and validation of psychedelic-induced insights and revelations. 2022 Theoretical or philosophical paper

Citations in the library

Cited by 16

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Cites 30

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