Neuroestimulantes naturales: de rituales ancestrales a terapias de vanguardia
Armando Ordaz‐hernández, M. Corona-Ramírez, Israel Jesús Orlando Guerrero
Revista CienciaUANL July 1, 2026 DOI: 10.29105/cienciauanl29.138-5 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Population | General population |
| Topics | Addiction |
| Keywords | Mental health Clinical practice Psychotherapist |
| Key findings | Psilocybin and 5-MeO-DMT show promise as therapies for depression, anxiety, PTSD, and addiction by acting on serotonin receptors and stimulating neuroplasticity. |
Abstract
La psilocibina, presente en los “hongos mágicos”, y la 5-MeO-DMT, secretada por el sapo Incilius alvarius, fueron empleadas ancestralmente en rituales espirituales en México. Hoy, la ciencia las reconoce como terapias prometedoras contra depresión, ansiedad, estrés postraumático y adicciones resistentes a tratamientos convencionales. Actúan sobre receptores de serotonina y estimulan la neuroplasticidad, favoreciendo la adaptación y la superación de patrones mentales negativos. Aunque se requieren más estudios clínicos, su uso ancestral inspira terapias innovadoras que integran tradición y ciencia para mejorar el bienestar emocional (Kishon et al., 2024). Abstract Psilocybin, found in “magic mushrooms,” and 5-MeO-DMT, secreted by the Incilius alvarius toad, were ancestrally used in spiritual rituals in Mexico. Today, science recognizes them as promising therapies for depression, anxiety, post-traumatic stress disorder, and addictions resistant to conventional treatments. They act on serotonin receptors and stimulate neuroplasticity, promoting adaptation and the overcoming of negative mental patterns. Although further clinical studies are needed, their ancestral use inspires innovative therapies that integrate tradition and science to improve mental health (Kishon et al., 2024).
Comparable studies
Other narrative reviews on addiction, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Classic psychedelics: An integrative review of epidemiology, therapeutics, mystical experience, and brain network function. General population | 2019 | Integrative review | |
| Mindfulness meditation–based pain relief: a mechanistic account | 2016 | Review | |
| Psychedelics as anti-inflammatory agents Animal models and cellular studies | 2018 | Review | |
| A narrative review of yoga and mindfulness as complementary therapies for addiction. | 2013 | Review | |
| The neuropsychopharmacology of cannabis: A review of human imaging studies | 2018 | Review |
Citations in the library
Cites 5
- Psilocybin: from ancient magic to modern medicine The Journal of Antibiotics May 12, 2020
- Efficacy and safety of psychedelics for the treatment of mental disorders: A systematic review and meta-analysis. Psychiatry Research May 1, 2024
- A phase 1/2 trial to assess safety and efficacy of a vaporized 5-methoxy-N,N-dimethyltryptamine formulation (GH001) in patients with treatment-resistant depression Frontiers in Psychiatry June 20, 2023
- A rapid narrative review of the clinical evolution of psychedelic treatment in clinical trials. npj Mental Health Research July 2, 2024
- Current Understanding on Psilocybin for Major Depressive Disorder: A Review Focusing on Clinical Trials Clinical Psychopharmacology and Neuroscience November 30, 2023