Catatonia Associated With First-Time Psilocybin Exposure: A Case Report
Jasbir Singh, Pranathi Mruthyunjaya
Cureus April 5, 2026 DOI: 10.7759/cureus.106474 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A 28-year-old male patient |
| Intervention | Psilocybin |
| Duration | Six months |
| Topics | Psilocybin |
| Citations | 1 |
| Key findings | Psilocybin ingestion can induce catatonia in individuals without prior psychiatric or substance use history. |
Abstract
In this case report, we highlight a 28-year-old male patient with predominantly retarded type of catatonia following a single incidence of psilocybin ingestion. This patient presented with a history of six months of mutism and inability to feed himself after consuming psilocybin for the first time. He did not have any history of psychiatric illness or substance use. Imaging and laboratory results were unremarkable. The goal of this case report is to document one of the earliest records of psilocybin-induced catatonia.