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Suicide of a patient shortly after psilocybin-assisted psychedelic therapy: A case report

Felix Müller, Thomas Sauer, Corina Hänny, Markus Mühlhauser, Undine E. Lang

Psychiatry Research January 29, 2025 DOI: 10.1016/j.psychres.2025.116381 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population 60-year-old man with recurrent depression and history of delusions
Intervention psilocybin-assisted therapy
Topics Psilocybin Psychedelic-assisted therapy
Keywords Hallucinogen Telepathy Psychotherapist Alternative medicine
Citations 11
Key findings Psilocybin-triggered delusions and emotional dysregulation may have contributed to the death of a patient with recurrent depression and history of delusions.

Abstract

• A 60-year-old man with recurrent depression and history of delusions died after psilocybin-assisted therapy. • Psilocybin-triggered delusions and emotional dysregulation may have contributed. • Weak therapeutic alliance hindered assessment of patient's internal state. • Delusional symptoms may contraindicate psychedelic interventions. • This case emphasizes the need for thorough assessment and close follow-up in complex cases.

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