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Effects of Transcendental Meditation in Veterans of Operation Enduring Freedom and Operation Iraqi Freedom With Posttraumatic Stress Disorder: A Pilot Study

Joshua Z. Rosenthal, Sarina Grosswald, Richard J Ross, Norman Rosenthal

Military Medicine June 1, 2011 DOI: 10.7205/milmed-d-10-00254 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Uncontrolled pilot study Placebo-controlled Peer reviewed
Sample size 5
Population Veterans from Operation Enduring Freedom or Operation Iraqi Freedom with combat-related PTSD
Intervention Transcendental meditation
Duration 12-week follow-up
Topics Meditation PTSD
Citations 98
Key points All five veterans improved on the primary PTSD symptom measure after 12 weeks of transcendental meditation, with a mean change score of 31.4 on the Clinician Administered PTSD Scale.

Abstract

We conducted an uncontrolled pilot study to determine whether transcendental meditation (TM) might be helpful in treating veterans from Operation Enduring Freedom or Operation Iraqi Freedom with combat-related posttraumatic stress disorder (PTSD). Five veterans were trained in the technique and followed for 12 weeks. All subjects improved on the primary outcome measure, the Clinician Administered PTSD Scale (mean change score, 31.4; p = 0.02; df = 4). Significant improvements were also observed for 3 secondary outcome measures: Clinician's Global Inventory-Severity (mean change score, 1.60; p < 0.04; df = 4), Quality of Life Enjoyment and Satisfaction Questionnaire (mean change score, -13.00; p < 0.01; df = 4), and the PTSD Checklist-Military Version (mean change score, 24.00; p < 0.02; df = 4). TM may have helped to alleviate symptoms of PTSD and improve quality of life in this small group of veterans. Larger, placebo-controlled studies should be undertaken to further determine the efficacy of TM in this population.

Comparable studies

Other non-randomized and open-label trials on PTSD, most cited first.

Study Year Design Participants
Durability of improvement in post-traumatic stress disorder symptoms and absence of harmful effects or drug dependency after 3,4-methylenedioxymethamphetamine-assisted psychotherapy: a prospective long-term follow-up study. Adults with chronic, treatment-resistant PTSD 2013 Long-term follow-up of a completed trial n = 19
Loving‐Kindness Meditation for Posttraumatic Stress Disorder: A Pilot Study Veterans with posttraumatic stress disorder (PTSD) 2013 Open pilot trial
MDMA-facilitated cognitive-behavioural conjoint therapy for posttraumatic stress disorder: an uncontrolled trial. Couples in which one partner was diagnosed with PTSD 2020 Pilot study n = 6
Culturally informed research design issues in a study for MDMA-assisted psychotherapy for posttraumatic stress disorder People of color with posttraumatic stress disorder 2019 Phase 2 open-label multisite study
Loving-Kindness Meditation and the Broaden-and-Build Theory of Positive Emotions Among Veterans With Posttraumatic Stress Disorder Veterans with active posttraumatic stress disorder (40% female) 2014 Open-pilot trial n = 42

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