Ibogaine: Revisiting an Ancient Alkaloid for Modern Opioid Dependence
Markus D Moore, Andrew Moore, Saeed K Alzghari
Substance Use & Misuse December 17, 2025 DOI: 10.1080/10826084.2025.2604213 (opens in new tab)
Study at a glance
AI-extracted from the abstractAbstract
Ibogaine is an interesting candidate that needs further study to determine its safety and potential for treating opioid dependence.
In the evidence
This study is part of the evidence base for a synthesis in the library. Here is how each one recorded it.
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Concludes that ibogaine is an interesting candidate that needs further study to determine its safety and potential for treating opioid dependence.
Synthesized
Comparable studies
Other narrative reviews on ibogaine for addiction, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| The Anti-Addiction Drug Ibogaine and the Heart: A Delicate Relation Humans, animals | 2015 | Review | |
| Ibogaine in the treatment of substance dependence. | 2013 | Review | |
| Ibogaine, an anti-addictive drug: pharmacology and time to go further in development. A narrative review. | 2008 | Review | |
| A review of chemical agents in the pharmacotherapy of addiction. | 2002 | Review | |
| Engineering Safer Psychedelics for Treating Addiction. | 2021 | Review |