Treatment With (Es)ketamine in Catatonia
Pim B. van der Meer, Sebastiaan O Verboeket, Arjen J. C. Slooter, Jan W. Schoones, Martijn S. van Noorden, Metten Somers, Albert Batalla, Annemiek Dols
The Journal of Clinical Psychiatry October 13, 2025 DOI: 10.4088/jcp.25br15940 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review Peer reviewed |
|---|---|
| Interventions | Ketamine Esketamine |
| Topics | Ketamine Esketamine |
| Keywords | Catatonia Nmda receptor Medline Meta-analysis Depression economics Systematic review Anesthesia Electroconvulsive therapy studies |
| Key findings | Ketamine and esketamine may be beneficial for catatonia, but the evidence is limited and more research is needed. |
Abstract
Recent evidence suggests that NMDA receptor antagonists, such as ketamine, may offer benefit in catatonia. This systematic review was conducted to evaluate the efficacy and safety of ketamine and esketamine for catatonia.