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What are sweet dreams made of? Analysis of psychoactive substances into “gummies”: A retrospective descriptive study

Amira Trabsa, E. Monteagudo, D.d. Mariona, M. Grifell, Liliana Galindo, L. Hernández González, P. Quintana, Á. Palma, Pedro Fernández Santiago, David Sanagustín, Mireia Ventura, Marta Torrens

European Psychiatry April 1, 2017 DOI: 10.1016/j.eurpsy.2017.01.1777 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational study Peer reviewed
Sample size 9
Population Gummy formulations of psychoactive substances submitted to Energy Control in Spain from June 2014 to December 2015
Duration June 2014 to December 2015
Topics MDMA
Keywords Psychoactive substance Psychoactive drug Harm reduction Traditional medicine
Citations 2
Key findings Gummy formulations of psychoactive substances in Spain from 2014 to 2015 most frequently contained 25N-NBOMe, and 66.7% did not contain the expected drug.

Abstract

Introduction: Although psychoactive substances has a long history in recreational settings, research on its composition has focused only on tablets, crystal and powder, even though new formulation for new psychoactive substances are readily available for users.

Objectives: To describe the presence of psychoactive substances and its characteristics in new formulations which had not previously been found in samples delivered to Energy Control from 2014 to 2015 in Spain.

Methods: A total of 8324 samples were analysed from June 2014 to December 2015. Only those samples in gummy formulation were studied ( n = 9). Samples were analyzed by energy control, a Spanish harm-reduction NGO that offers analysis of substances to users. Analysis was done by gas chromatography-mass spectrometry.

Results: From 9 samples of psychoactive substances in gummy formulation, the analysis detected that 55.5% contained multiple psychoactive substances: 6 samples contained 25N-NBOMe (66.7%), 1 2C-E (11.1%), 1 2C-D (11.1%). Two allylescaline (20%), 1 cocaine (11.1%), 1 THC (11.1%), 1 canabinol (11.1%), 1 ketamine (11.1%), 1 caffeine (11.1%), 1 MDMA (11.1%), 1 N-acetyl-MDMA (11.1%), 1 metoxetamine (11.1%), 1 N-acetyl-MDMA), 1 2C-N (11.1%). The only substance found in active dosage was 25N-NBOMe. Six samples (66.67%) did not contain the substance expected by the consumer.

Discussion: Incipient presence of gummies as new psychoactive formulation was found. The most prevalent drug was 25N-NBOMe; 66.7% did not contain the substance expected. This may pose a risk for potential harmful effects. All the gummies were known to be drug-carriers when bought. This could represent the presence of new formulations from June 2014 in the Spanish recreational market. Disclosure of interest The authors have not supplied their declaration of competing interest.

Comparable studies

Other observational and cohort studies on MDMA, most cited first.

Study Year Design Participants
Subjective Reports of the Effects of MDMA in a Clinical Setting Individuals who took MDMA in a clinical setting 1986 Observational study
Memory impairment in abstinent MDMA ("Ecstasy") users Abstinent MDMA users 1998 Observational cohort
Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) Otherwise healthy young people 2000 Observational
The Psychological and Physiological Effects of MDMA on Normal Volunteers Older, more educated, drug-experienced individuals 1986 Observational cohort
Cognitive performance in recreational users of MDMA or 'ecstasy': evidence for memory deficits Young people who were regular or novice MDMA users, or non-users 1998 Observational cohort n = 30

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