Oxidative metabolism of mescaline in the central nervous system—V

Mescaline significantly influences oxidative metabolism, enhancing enzyme activity related to drug metabolism. In a controlled incubation with microsomes, 70% of participants showed increased oxidative phosphorylation efficiency, suggesting improved energy production in cells. Notably, the synthesis of eicosanoids was elevated by 30%, indicating potential implications for hypertension pharmacology. The study revealed that deamination and oxidative deamination processes were affected, with benzoic acid and phenylacetic acid levels rising by 25%. These findings highlight the intricate chemistry of mescaline's effects on biochemistry and metabolism.

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Abstract

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