Psychoactive Properties of Alpha-Methyltryptamine: Analysis From Self Reports of Users
Journal of Psychoactive Drugs July 1, 2012 DOI: 10.1080/02791072.2012.704592 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Retrospective survey Peer reviewed |
|---|---|
| Population | Former users of alpha-methyltryptamine (AMT) |
| Intervention | alpha-methyltryptamine |
| Topics | Anxiety |
| Keywords | Dysphoria Nausea Depression economics Hallucinogen Clinical psychology |
| Citations | 19 |
| Key findings | AMT has strong hallucinogenic qualities and is associated with anxiety, nausea, dysphoria, and depression, posing risks for individuals prone to depression. |
Abstract
This is a retrospective examination of former users of alpha-methyltryptamine (AMT). A scale of questions was given to subjects who were familiar with the effects of AMT and the outcome was analyzed. Most subjects agreed that AMT had strong hallucinogenic qualities. The most common unwanted effects included anxiety, nausea and moderately severe dysphoria. Several subjects reported significant depression associated with use of AMT. Use of alpha-methyltryptamine could be dangerous in individuals prone to depression.
Comparable studies
Other cross-sectional and survey studies on anxiety, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety. International sample of people who reported having used a psychedelic | 2020 | Cross-sectional survey | n = 985 |
| The Challenging Experience Questionnaire: Characterization of challenging experiences with psilocybin mushrooms Internet survey respondents reporting challenging experiences with psilocybin | 2016 | Questionnaire development and validation | |
| Psychedelics and Mental Health: A Population Study Adult population in the United States | 2013 | Cross-sectional survey | n = 130,152 |
| Ecstasy/MDMA attributed problems reported by novice, moderate and heavy recreational users Ecstasy users who participated in a WWW study of recreational drug use | 2002 | Cross-sectional survey | n = 282 |
| 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) used in a naturalistic group setting is associated with unintended improvements in depression and anxiety. Adults who used 5-MeO-DMT in a group setting with structured procedures | 2019 | Cross-sectional survey | n = 362 |
Citations in the library
Cited by 9
- Novel psychoactive substances of interest for psychiatry World Psychiatry February 1, 2016
- Recreational Use, Analysis and Toxicity of Tryptamines Current Neuropharmacology December 10, 2014
- Toxicology and Analysis of Psychoactive Tryptamines International Journal of Molecular Sciences December 4, 2020
- 5‐(2‐Aminopropyl)indole (5‐IT): a psychoactive substance used for recreational purposes is an inhibitor of human monoamine oxidase (MAO) Drug Testing and Analysis September 20, 2013
- Patterns of presentation and clinical toxicity after reported use of alpha methyltryptamine in the United Kingdom. A report from the UK National Poisons Information Service Clinical Toxicology February 28, 2014
and 4 more in the library
Cites 4
- Fatality Due to Acute α-Methyltryptamine Intoxication Journal of Analytical Toxicology July 1, 2005
- Abuse Liability Profile of Three Substituted Tryptamines Journal of Pharmacology and Experimental Therapeutics April 8, 2011
- COMPARISON OF THREE PSYCHOTROPIC DRUGS (PSILOCYBIN, JB-329, AND IT-290) IN VOLUNTEER SUBJECTS The Journal of Nervous and Mental Disease November 1, 1960
- Indolealkylamine analogs share 5-HT2 binding characteristics with phenylalkylamine hallucinogens. European Journal of Pharmacology 1988