Treatment and outcomes at Takiwasi Center, a Peruvian therapeutic community: identifying patient-related indicators
Victoria Defelippe, Anna Schlütter, Annelen Meriaan, Björn Winkens, Veronika Kavenská, Gary Saucedo Rojas, Matteo Politi
Therapeutic Communities: The International Journal of Therapeutic Communities May 30, 2019 DOI: 10.1108/tc-07-2018-0016 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Sample size | 121 |
| Population | Patients in ayahuasca-assisted addiction therapy at Takiwasi centre (2012-2017) |
| Topics | Addiction |
| Keywords | Logistic regression Substance abuse Addiction treatment Odds ratio Family medicine |
| Citations | 7 |
| Key findings | Students had significantly higher odds of treatment non-completion compared to employed patients (OR=3.7, 95% CI=1.5–9.6, p=0.006), while other variables showed no significant association. |
Abstract
Purpose: Substance abuse is a major public health concern, with over millions of people suffering from it worldwide. Although there is an abundance of treatment options, many of these rehabilitative trajectories are subject to “drop-out”. In addition, “drop-out” is a significant risk factor for relapse. There is an urgent demand for effective treatment, which would enable patients to reduce abuse and prevent relapse. Takiwasi is an addiction treatment centre that combines traditional Amazonian plant medicine with conventional western medicine and psychotherapy. The purpose of this paper is to explore whether socio-demographics factors, such as education level and occupation, psychiatric comorbidities and primary drug use, are associated with treatment non-completion of Ayahuasca (AYA)-assisted addiction therapy. Design/methodology/approach Data on the first treatment episode of 121 patients were collected from the patient database from the years 2012 to 2017. To determine whether there is an association between the variables of interest and treatment non-completion, a χ 2 analysis and a logistic regression analysis were performed.
Findings: Of the 121 patients analysed, 48.2 per cent completed their treatment, whilst 51.8 per cent did not. Students compared to those who are employed showed significantly higher odds for treatment non-completion ( p =0.006; OR=3.7; 95% CI=1.5–9.6). Other variables in the multivariable analysis showed no significant relationship with treatment non-completion. While several limitations restricted the study, the findings suggest that the AYA-assisted treatment in Takiwasi may benefit from additional support for patients who are students. Moreover, it is advised to conduct more long-term follow-up of patients in order to gain better insight into the outcome of treatment at an AYA-assisted treatment centre. Originality/value It appears that AYA-assisted therapy in a therapeutic community is a feasible type of treatment for addiction, for which further studies should elucidate the role of motivation in relation to socio-demographic factors and type of addiction in the risk of treatment non-completion.
Comparable studies
Other observational and cohort studies on addiction, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Rural aboriginal population | 2013 | Observational study | |
| Dynamic coupling of whole-brain neuronal and neurotransmitter systems Healthy humans | 2020 | Observational study | |
| Psychedelics not linked to mental health problems or suicidal behavior: A population study Randomly selected United States adults | 2015 | Observational cohort | n = 135,095 |
| Breakdown of long-range temporal dependence in default mode and attention networks during deep sleep Human participants across the nonrapid eye movement sleep cycle | 2013 | Observational cohort | |
| Assessment of addiction severity among ritual users of ayahuasca Regular ayahuasca users (jungle-based and urban-based) and matched controls | 2010 | Observational cohort | n = 127 |
Citations in the library
Cited by 4
- Protocol for Outcome Evaluation of Ayahuasca-Assisted Addiction Treatment: The Case of Takiwasi Center Frontiers in Pharmacology May 19, 2021
- Traditional Knowledge and Therapeutic Application of Chiric Sanango (Brunfelsia grandiflora) in an Amazonian Rehabilitation Center. Journal of Psychoactive Drugs January 15, 2026
- Producción científica en Scopus sobre el uso de ayahuasca en la salud humana: Estudio Bibliométrico Anales de la Facultad de Medicina September 9, 2026
- Traditional Amazonian medicine in addiction treatment: Qualitative results SSM: Qualitative Research in Health June 4, 2022
Cites 9
- Monoamine oxidase inhibitors in South American hallucinogenic plants: Tryptamine and β-carboline constituents of Ayahuasca Journal of Ethnopharmacology April 1, 1984
- Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Current Drug Abuse Reviews June 1, 2013
- The current state of research on ayahuasca: A systematic review of human studies assessing psychiatric symptoms, neuropsychological functioning, and neuroimaging Journal of Psychopharmacology June 11, 2016
- Ayahuasca’s entwined efficacy: An ethnographic study of ritual healing from ‘addiction’ International Journal of Drug Policy April 19, 2017
- Effects of Ayahuasca and its Alkaloids on Drug Dependence: A Systematic Literature Review of Quantitative Studies in Animals and Humans Journal of Psychoactive Drugs May 26, 2016
and 4 more in the library