Influence of Environmental Factors and Cultural Methods on the Content of N,N‑Dimethyltryptamine in Psychotria viridis (Rubiaceae)
André D. Cavalcante, Gabriele A. Cardoso, Fernando de Oliveira, Eduardo Bearzoti, Adriana Akemi Okuma, Lucienir Pains Duarte, Sidney Augusto Vieira Filho
Journal of the Brazilian Chemical Society 2017 DOI: 10.21577/0103-5053.20170221 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational study Peer reviewed |
|---|---|
| Population | Psychotria viridis leaf samples from 25 locations in Brazil |
| Duration | Over all four seasons |
| Topics | 5-MeO-DMT DMT |
| Keywords | Psychotria Rubiaceae Botany Alkaloids |
| Citations | 11 |
| Key findings | Seasonality, altitude, latitude, and biome type most strongly influence DMT content in Psychotria viridis, with nitrogen and magnesium levels positively correlated with DMT concentration. |
Abstract
Psychotria viridis is one of the species that produces N,N-dimethyltryptamine. Its decoction \ntogether with other species, such as Banisteriopsis caapi, produces ayahuasca, a beverage used for \nritualistic and medicinal purposes. The goal of this study was to understand how environmental \nfactors and cultivation methods influenced the content of N,N-dimethyltryptamine in P. viridis. \nOver all four seasons, leaf samples were collected from 25 different locations in 14 Brazilian \nstates, and Federal District. Environmental parameters, micro and macronutrients, plant \ncharacteristics, information on farming methods were correlated with N,N-dimethyltryptamine \ncontent, determined by gas chromatography coupled to mass spectrometry (GC-MS). Greatest \neffects on the N,N-dimethyltryptamine amount were associated with seasonality, altitude, latitude \nand biome type. A positive correlation between N and Mg content and N,N-dimethyltryptamine \nlevels was statistically established. By regression analysis, the adequate foliar nutrient levels that \nwould result in the concentration of N,N-dimethyltryptamine in cultivated plants similar to that \nof Amazonian P. viridis were equated.
Comparable studies
Other observational and cohort studies on DMT, most cited first.
Citations in the library
Cited by 4
- Assessment of environmental condition and drying process of the plants on the concentration of alkaloids and cytotoxicity of traditional Ayahuasca Tea World Journal of Advanced Research and Reviews May 21, 2021
- Plant dehydration, alkaloid concentration, and cytotoxicity on ayahuasca traditional tea Amazon Expedition Magazine. March 1, 2024
- Avaliação da variação morfológica, anatômica e fitoquímica de >i/i< (Spruce ex Griseb.) C.v. Morton e >i/i< Ruiz & Pav em diferentes ambientes, teor de alcaloides e citotoxicidade do chá Ayahuasca December 10, 2020
- Influence of environmental conditions and seasonality on the metabolome and lipidome of Psychotria viridis leaves. The Plant Journal July 1, 2025