Risk assessment of ayahuasca use in a religious context: self-reported risk factors and adverse effects
Ícaro Durante, Rafael G. Dos Santos, José Carlos Bouso, Jaime E. C. Hallak
Brazilian Journal of Psychiatry October 30, 2020 DOI: 10.1590/1516-4446-2020-0913 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational study Peer reviewed |
|---|---|
| Population | Participants in ayahuasca rituals |
| Intervention | Ayahuasca |
| Topics | Anxiety Ayahuasca |
| Keywords | Adverse effect Context archaeology Nausea Depression economics Hallucinogen Pharmacology |
| Citations | 49 |
| Key findings | Psychiatric medication use during ayahuasca rituals was not associated with increased adverse effects, and institutional practices appear sufficient to prevent exacerbated reactions. |
Abstract
A minority of participants reported being very negatively affected by persistent adverse effects. Psychiatric medication use while participating in ayahuasca rituals was not associated with increased adverse effects. For the most part, the institution's practices seem sufficient to prevent exacerbated reactions. Future studies may focus on negatively affected users.
Comparable studies
Other observational and cohort studies on ayahuasca for anxiety, most cited first.
Citations in the library
Cited by 44
- Adverse effects of psychedelics: From anecdotes and misinformation to systematic science. Journal of Psychopharmacology February 2, 2022
- Adverse events in clinical treatments with serotonergic psychedelics and MDMA: A mixed-methods systematic review Journal of Psychopharmacology August 26, 2022
- Adverse effects of ayahuasca: Results from the Global Ayahuasca Survey. PLOS global public health 2022
- The Psychedelic Future of Post-Traumatic Stress Disorder Treatment Current Neuropharmacology January 5, 2024
- Cardiovascular safety of psychedelic medicine: current status and future directions Pharmacological Reports October 24, 2023
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Cites 21
- Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Brazilian Journal of Psychiatry March 1, 2015
- Human Psychopharmacology of Hoasca, A Plant Hallucinogen Used in Ritual Context in Brazil The Journal of Nervous and Mental Disease February 1, 1996
- Subjective effects and tolerability of the South American psychoactive beverage Ayahuasca in healthy volunteers Psychopharmacology February 22, 2001
- Classical psychedelics for the treatment of depression and anxiety: A systematic review. Journal of Affective Disorders November 1, 2019
- Neuropharmacology of N,N-dimethyltryptamine Brain Research Bulletin April 30, 2016
and 16 more in the library