Psychotherapy Process Dynamics and Their Relation to Treatment Success Do Not Differ Across Diagnoses.
Lennart Seizer, Leonhard Kratzer, Johanna Löchner, Helmut Schöller, Wolfgang Aichhorn, Günter Schiepek
Clinical Psychology & Psychotherapy 2026 DOI: 10.1002/cpp.70222 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Longitudinal Peer reviewed |
|---|---|
| Sample size | 283 |
| Population | Psychiatric inpatients diagnosed with depression, PTSD, dissociative disorders, or personality disorders |
| Duration | Average of 81.5 days per patient |
| Keywords | Ambulatory assessment Diagnostic categories Dynamic pattern Ecological momentary assessment Monitoring Psychotherapy Therapy process questionnaire Transdiagnostic |
| Citations | 1 |
| Key findings | No significant differences in dynamic process characteristics or their change over time were found across diagnostic groups, and clinical improvement was associated with rising mean levels and declining variability in positive emotions, mindfulness, insight, and motivation, regardless of diagnosis. |
Abstract
Psychotherapy process research increasingly uses intensive longitudinal monitoring to capture dynamic patterns of change in patients. In this study, 283 psychiatric inpatients diagnosed with depression (n = 70), PTSD (n = 148), dissociative disorders (n = 26) or personality disorders (n = 39) completed the Therapy Process Questionnaire each evening over an average of 81.5 days per patient, yielding a total of 23,074 assessment days. We computed eight dynamic process characteristics, including variability, autocorrelation, instability and complexity, for each TPQ scale, both on average per patient and in a moving-window approach. Then, the diagnostic groups were compared via one-way ANOVAs with Bonferroni-Holm correction. No significant differences emerged across diagnoses in any average process characteristics or their change over time, indicating that idiosyncratic within-person process dynamics overshadow diagnostic distinctions. Further, patients' clinical improvement was associated with rising mean levels and declining variability in positive emotions, mindfulness, insight and motivation. Again, these predictions of improvement were not moderated by patients' diagnoses. Our results support a transdiagnostic approach to measurement-based care that leverages individual process characteristics to guide interventions, rather than relying on diagnostic categories to predict therapy trajectories.