Prolonged hallucinogenic effects following Psilocybe cubensis ingestion: Case report
Rodrigo A. Petter, María D. Montero, Cinthia D. Gigliotti
The poison. June 30, 2025 DOI: 10.62129/dmad8764 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A person who ingested Psilocybe cubensis |
| Intervention | psychopharmacological intervention |
| Topics | Psilocybin |
| Keywords | Hallucinogen Ingestion Traditional medicine Pharmacology Alkaloids |
| Key findings | Prolonged perceptual disturbances and flashbacks can occur weeks after psilocybin ingestion, requiring psychopharmacological intervention. |
Abstract
Psilocybe cubensis is a widely used psilocybin-containing mushroom with well-documented acute psychoactive effects. We report a case of prolonged perceptual disturbances and flashbacks occurring weeks after ingestion, requiring psychopharmacological intervention. This case illustrates the potential for persistent neuropsychiatric symptoms following psilocybin intoxication and highlights the need for individualized treatment approaches. Given the increasing recreational use of psilocybin, enhanced harm reduction strategies and expanded clinical research are essential for effective management.
Comparable studies
Other case reports and case series on psilocybin, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Psilocybin Mushroom (Psilocybe semilanceata) Intoxication with Myocardial Infarction 18-year-old man | 1998 | Case study | n = 1 |
| Relief from intractable phantom pain by combining psilocybin and mirror visual-feedback (MVF) Person with leg amputation and phantom-limb pain | 2018 | Case study | n = 1 |
| Hallucinogen persisting perception disorder after psilocybin consumption: a case study 18-year-old man with HPPD after mixed psilocybin and cannabis intoxication | 2005 | Case study | n = 1 |
| Microdosing psilocybin for chronic pain: a case series Individuals with chronic neuropathic pain | 2022 | Case series | n = 3 |
| Psilocybin and Obsessive Compulsive Disorder Individual with Obsessive Compulsive Disorder | 2014 | Case study | n = 1 |