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Prolonged hallucinogenic effects following Psilocybe cubensis ingestion: Case report

Rodrigo A. Petter, María D. Montero, Cinthia D. Gigliotti

The poison. June 30, 2025 DOI: 10.62129/dmad8764 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population A person who ingested Psilocybe cubensis
Intervention psychopharmacological intervention
Topics Psilocybin
Keywords Hallucinogen Ingestion Traditional medicine Pharmacology Alkaloids
Key findings Prolonged perceptual disturbances and flashbacks can occur weeks after psilocybin ingestion, requiring psychopharmacological intervention.

Abstract

Psilocybe cubensis is a widely used psilocybin-containing mushroom with well-documented acute psychoactive effects. We report a case of prolonged perceptual disturbances and flashbacks occurring weeks after ingestion, requiring psychopharmacological intervention. This case illustrates the potential for persistent neuropsychiatric symptoms following psilocybin intoxication and highlights the need for individualized treatment approaches. Given the increasing recreational use of psilocybin, enhanced harm reduction strategies and expanded clinical research are essential for effective management.

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