Diminished psychedelic returns on distress: Marital status and household size
PLoS One March 7, 2024 DOI: 10.1371/journal.pone.0293675 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational study using pooled cross-sectional data Peer reviewed |
|---|---|
| Sample size | 158,633 |
| Population | Respondents to the National Survey of Drug Use and Health (NSDUH) from 2010 to 2018 |
| Keywords | Marital status Affect linguistics Logistic regression Demography Distress Association psychology Sample size determination Gerontology Environmental health Clinical psychology Population |
| Citations | 14 |
| Key findings | Household size negatively moderates the association between lifetime classic psychedelic use and psychological distress, with the worst outcomes among married, divorced, and widowed users in larger households. |
Abstract
Although the use of psychedelics to impact health has seen growth, little research has tested the effects of culture conditions on the relationship. More specifically, how does marital status and family size affect the relationship between psychedelics and health? This study tests the relationship between Lifetime Classic Psychedelic Use (LCPU), marital status, and household size (number of people living in a household) on levels of psychological distress in the past 30 days. This project uses pooled data from the National Survey of Drug Use and Health (NSDUH) (2010 to 2018) ( N = 674,521). The Final sample size is determined by the dependent variable, psychological distress in the past month (n = 158,633). The analysis includes a series of nested logistic regression models conducted in Stata 17. Results indicate that LCPU is independently associated with better health, but the association between LCPU and health varies across levels of household size. Larger households are associated with higher levels of distress, which are then exacerbated among psychedelics users. Furthermore, three-way interactions reveal that the negative association between household size and distress gets larger among psychedelic users who are married, divorced, and widowed. Overall, results suggest that household size negatively impacts the association between LCPU and health, with those who are married, divorced, and widowed experiencing the worst outcomes.
Citations in the library
Cited by 12
- Minorities' Diminished Psychedelic Returns: Income and Educations Impact on Whites, Blacks, Hispanics, and Asians. Journal of Racial and Ethnic Health Disparities June 1, 2025
- Religion, Psychedelics, Risky Behavior, and Violence. Journal of Psychoactive Drugs 2025
- Minorities’ Diminished Psychedelic Returns: Gender, Perceived Stigma, and Distress Psychoactives June 2, 2024
- Race and Gender Differences in the Moderating Relationship of Psychedelics on Stigma and Distress Psychedelic Medicine April 22, 2025
- Religious Social Integration, Psychedelics, and Psychological Distress. Journal of Psychoactive Drugs November 7, 2024
and 7 more in the library
Cites 45
- Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Journal of Psychopharmacology November 30, 2016
- Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Journal of Psychopharmacology November 30, 2016
- Trial of Psilocybin versus Escitalopram for Depression New England Journal of Medicine April 14, 2021
- Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder JAMA Psychiatry November 4, 2020
- Psychedelics Promote Structural and Functional Neural Plasticity Cell Reports June 1, 2018
and 40 more in the library